Cataracts are primarily a disease of ageing. Instead of an operating to remove them, researchers are trying to make a cataract-dissolving-eye drops which can break down cataracts and restore transparency of the lens and vision. Cataracts can be successfully removed with surgery, but this method is costly, and most individuals blinded by severe cataracts in developing countries go untreated. A characteristic of the condition is the mis-folding and clumping together of crucial proteins known as crystallins. So that our lenses are able to function well, crystallins (which we are born and live our whole lives with) must maintain both the transparency of fibre cells and their flexibility as the eyes' muscles constantly stretch and relax the lens to allow us to focus on objects at different distances. Scientists at the University of California San Francisco exploited a key difference between correctly folded crystallins and their amyloid forms; finding that amyloids are much harder