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One Paragraph on Biological Heart Pacemakers | One Paragraph Science

Patients with heart problems sometimes experience issues with regulating their heart beat and often require artificial pacemakers. but the problem with artificial pacemakers is that they aren't that great anymore and have to be checked and replaced periodically. A review article published on November 20 in Trends in Molecular Medicine highlights the promise and limitations of new methods based on stem cell and reprogramming technologies to generate biological pacemakers that might one day replace electronic pacemakers. Biological pacemakers, which are composed of electrically active cells, can functionally integrate with the heart and could provide natural heart rhythm regulation without the need for indwelling hardware. One way to work with stem cells; scientists can coax the stem cells into becoming cells found in the SAN (Sino-Atrial Node). The second way to work with stem cells; by directly programming supporting cells, already present in the heart - for example, fibroblas

Stem Cells Do What They Do Because They Discriminate

Stem cells are the clean slates of the human body. They're the cells (usually found in bone marrow) that are stored till they have a significant job. Stem cells remain stem cells until they need to differentiate into a specific type of cell i.e  a heart cell, a kidney cell or even a skin cell. New research goes into the way stem cells differentiate and what goes into the process. The study (conducted by the Institute of Biotechnology and Massachusetts Institute of Technology (MIT)) suggests that asymmetric apportioning of old cellular components during cell division may represent an anti-aging mechanism utilized by stem cells. They focus on tissue stem cells, that continuously renew our tissues which divide asymmetrically to produce 2 types of daughter cells: one a new stem cell, the second one will become the differentiating cell of a tissue. Stem cells undergo this technique to prevent cellular damage. Extra damage can cause stem cell fatigue and less tissue regeneration an